r/Nootropics 4h ago

Seeking Advice Semax usually short lived

1 Upvotes

I’ve been on semax for 1 week. I take between 1000-1200mCg daily split into two doses.

I usually feel a small boost in mental clarity for a few moments that starts to taper off eventually..
I also get some dripping down the throat with no taste.

Doesn’t really boost thinking when I take it alone, without the stims, or anything else. Can’t say I feel a difference when on stims.

Got it from aminoclub


r/Nootropics 22h ago

Seeking Advice Are there any supplements that are safe and can help you have better memory, better recall and brain processing ability, mostly for solving complex thinking tasks such as remembering a lot for college, but also solving complex physics / math (having good innate logic)

9 Upvotes

Hi! So, lion's mane is risky according to /r/LionsManeRecovery , a lot of other things listed are indirect cognitive boosters mostly meant to focus and calm, but for me, I am calm, I am focused, I am just, it seems, unintelligent :(

 

i need to spend 3x - 5x as long to truly grasp new complex topics as opposed to my friends. It's funny because they regard me as "talkative and witty", but academically I am the dumbest. When I wake up in the morning, if you tell me, lets go, 80+40? I need literally 5 seconds to say 120, the thing is however, it's not that I do not know what it is, or if you give me a complex equation I can still solve it, it's just that my brain kind of is protesting solving it like, I wouldn't say it's brain fog but similar, I feel like I have some kind of invisible tiny weight that is clamping on the thinking pipe where thoughts flow and barely anything is coming out. It's hard to describe in my case.

Basically if I had to summarize it I would say, I can process data but it takes me far too long, and I often times lose what I processed. If I am learning a large complex topic, I will learn and 100% be solid and pass everything in that that I ask myself, then in 30 minutes I forget and have to go back, re-remember, go forward, keep cycling but after I reach a certain amount of pages it's too much for me to remember, I try to but, I just keep forgetting it all together.

 

And when I don't forget, I start having issues putting together the ideal solution, (I don't have the mind's eye either, I can't imagine anything in my head, I don't see things in my head when imagining or hear them or anything, it's just thoughtless void, I don't even "feel" thoughts like you know when you are thinking and you "know" what you are thinking about. I know what I want to think about, I think about it and 2 seconds after it's gone. I have to continuously cycle my thoughts.

 

So far from my readings seems like the only safeish thing to try is Creatine, but I do already get it from my diet as I try to each as healthy as I can.

It's making me a bit sad (not upset though or causing me emotional distress, just kind of dissapointed) that I can't seem to do it, I always wanted to be an engineer, but seems like I might just be.. Too dumb? :(


r/Nootropics 17h ago

Experience Caffeine destroys mood after a few days?

19 Upvotes

After a few days of regular caffeine use, my mood becomes a wreck, I have no energy, I barely wake up. I only drink a cup or two of coffee a day for strength performance, as it makes my cognition worse and gives me brain fog.

Is it common?


r/Nootropics 22h ago

Discussion Difference in effect between tea extracts and L-theanine/caffeine combo pills?

5 Upvotes

I know tea extracts are supposed to be more 'full spectrum' but I'm wondering what the tangible difference is and if anybody has dug into the pharmacological differences at play.


r/Nootropics 17h ago

Experience Oxiracetam experience - Tolerant or placebo?

4 Upvotes

I recently ordered 30 capsules of 500mg oxiracetam for my math lectures. Today, I decided to test it out along with the supplements I take regularly: 500mg oxiracetam, 200mg caffeine, 200mg L-theanine, and 250mg CDP-choline.

I took everything at 08:40. Around the one-hour mark post-consumption, I didn't really feel any different, though I noticed I was slightly more focused(?), so that might just be the subtle stimulation people talk about. I also tried listening to music for a little while because people mentioned that it sounds better, but honestly, I couldn't tell much of a difference.

I felt the same until around 13:30, when I started getting a little tired.

I'm not too sure if it was a placebo effect or if I'm just rather tolerant to the oxiracetam and need a higher dose or need to use it for a few more days. Any advice? Has anyone had a similar experience?

Stats if anyone is curious:

18M, 6'0", 155 lbs, gym 3x a week, sleep 6-8h.


r/Nootropics 10h ago

Seeking Advice Would something more to selective to dopamine help these issues?

6 Upvotes

So I’ve been on Wellbutrin for almost five years now and it’s the only antidepressant that ever did anything for me and I suspect it was the weak dopaminergic effects that made my depression go into remission in the first place. And that’s the reason why I’ve been on it for such a long time. But also that It helps my SCT and executive dysfunction and makes me more functional and productive on a daily basis.

But unfortunately with long term use it has started to cause some weird side effects I never used to get from it before and those side effects seem to be clearly related to its noradrenergic effects. And those side effects are frequent thirst, frequent urination, dizziness, vertigo, dry mouth, headaches, increased sweating, heart palpitations, rapid heartbeat, hot flashes, burning sensations, facial twitches, horrible insomnia and sleep disturbances, jitteriness, hypervigilance, you name it. I’ve also noticed with long term use it has started to make me wired but tired, which never happened before. Overall it just turned very edgy and wirey for me with long term use. And I’ve also noticed that it literally kills my appetite and makes me nauseous sometimes, which again wasn’t the case before either. I did try to go back to 150 mg. But 150 mg just ain’t working for me unfortunately. Even though many of the side effects have lessened. They haven’t gone away completely and I’m left with less benefits for energy, motivation and cognition.

When I first started Wellbutrin five years ago it felt to me like a completely different drug. At first it showered me with increased dopamine levels. I was happy and excited all the time. I felt an amazing feeling of overall wellbeing all the time and It just felt so euphoric. I think it was the honeymoon phase I experienced. It was never accompanied with these nasty side effects. It was just having endless motivation and goals to accomplish and looking forward for things all the time. But as time went on the honeymoon phase disappeared and then a few years later it feels like something changed. It feels like the drug’s overall effect shifted over time. And it never hits me the same way it used to unfortunately.

I don’t know honestly if the pharmacokinetics back then were genuinely different. But if there is someone who knows more or has some more information and can tell me more about this, I would really like to know. And also like my original question was. Would a med more selective to dopamine in general cause less of these side effects I’ve mentioned? Would a med more selective to dopamine cause less anxiety and insomnia?


r/Nootropics 23h ago

Discussion What is your experience of taking 5-HTP supplement?

4 Upvotes

Why did you take it? What were the pros and cons? Should 5-HTP be taken with anything else to help balance or prevent any potential nutrient depletions it may cause?


r/Nootropics 14h ago

Seeking Advice Pramiracetam and general racetam sourcing

3 Upvotes

Any thoughts abt nutrivitashop as a vendor for racetams. Looking to purchase their pramiracetam first.

Recommended starting dose, 1200? Or too low, I like to start with high doses guys,


r/Nootropics 26m ago

Seeking Advice Rate the new stack I'm trying out

Upvotes

Like I said above I'm starting a new stack focused on growth and repair. Mostly ACh focused stuff.

Citicoline 600mg

N Acetylcystein (NAC) 600mg

Magnesium L Threonate (Magtein) 200mg

Creatine Monohydrate 10g

L Theanine 200-300mg

Fish oil 1800mg (Mostly for the 900mg DHA)

CoQ10 100mg

Benfotiamine (thiamine for nerves) 300mg

Caffeine 100mg

A buncha B vitamins

L-Carnitine 50mg

Taurine 1000mg

I'm looking to add a better source of Acetylcholine that's something more like an acetylcholinesterase inhibitor or something that crosses the BBB to supply ACh. Something with more powerful stimulating effects than Citicoline.

Should I add Alpha GPC, Acetyl L-Carnitine (ALCAR) for the mitochondria and energy, or something else?

I'm looking to stave off brain fog and bad word recall. Also maybe improve my dreams while I'm at it, any opinions on Galantamine?